...Nicoud and M. Perrut, “High Pressure Chemical Engineering...

来自 : www.oalib.com/references/7470. 发布时间：2021-03-25

This work shows how the sesamin and sesamolin in sesameseed can be extracted, enriched and purified by the related technologies ofsupercritical carbon dioxide. Sesame oil is first obtained from the sesameseeds by supercritical carbon dioxide extraction (SFE); lignans in the oil areenriched and precipitated as the top product by supercritical fluid fractionationtechnology (SFF); the crude lignans are then separated by supercritical fluid-simulatedmoving bed chromatography (SF-SMB) to obtain pure sesamin and sesamolin. The simulatedmoving bed is a continuous chromatography; the use of supercritical carbondioxide as the desorbent simplifies the downstream treatment. By experimentalvalidation, this work also shows that replacing liquid by SF as thedesorbent for the SMB automatically creates a gradient operation for the SMBand enlarges the separable range of the operating conditions. Both the design andoperation of the SF-SMB are introduced in this paper. The application of SF-SMBto the separation of sesamin and sesamolin provides a novelexample for demonstrating the diversity of SF and the potential applications forthe production of natural products and the development of botanical drugs.
Trepp, Eds., A New Efficient Fractionation Process: The Simulated Moving Bed with Supercritical Eluent, Elsevier Science, London, 1996, pp. 429-434...J. Y. Clavier, R. M. Nicoud and M. Perrut, “High Pressure Chemical Engineering,” In: Ph. R. von Rohr and Ch. Trepp, Eds., A New Efficient Fractionation Process: The Simulated Moving Bed with Supercritical Eluent, Elsevier Science, London, 1996, pp. 429-434.J. Y. Clavier, R. M. Nicoud and M. Perrut, “High Pressure Chemical Engineering,” In: Ph. R. von Rohr and Ch. Trepp, Eds., A New Efficient Fractionation Process: The Simulated Moving Bed with Supercritical Eluent, Elsevier Science, London, 1996, pp. 429-434.J. Y. Clavier, R. M. Nicoud and M. Perrut, “High Pressure Chemical Engineering,” In: Ph. R. von Rohr and Ch. Trepp, Eds., A New Efficient Fractionation Process: The Simulated Moving Bed with Supercritical Eluent, Elsevier Science, London, 1996, pp. 429